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Primate Biology An international open-access journal on primate research
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PB | Articles | Volume 6, issue 2
Primate Biol., 6, 75–86, 2019
https://doi.org/10.5194/pb-6-75-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
Primate Biol., 6, 75–86, 2019
https://doi.org/10.5194/pb-6-75-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.

Research article 29 Jul 2019

Research article | 29 Jul 2019

Baboon induced pluripotent stem cell generation by piggyBac transposition of reprogramming factors

Ignacio Rodriguez-Polo et al.
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The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells but is not a general stem cell marker
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The ubiquitin ligase c-CBL is expressed in undifferentiated marmoset monkey pluripotent stem cells but is not a general stem cell marker
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Primate Biol., 4, 153–162, https://doi.org/10.5194/pb-4-153-2017,https://doi.org/10.5194/pb-4-153-2017, 2017
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Stem-cell-based regenerative therapies in patients, e.g., for a failing heart or Parkinson's disease, are within reach. However, studies in appropriate animal models are required to make the final step to the clinic. In this context, the baboon may represent a valuable animal model for specific purposes. Here, we generated five so-called induced pluripotent stem cell lines from the baboon, which may be useful for preclinical testing of the respective therapeutic approaches.
Stem-cell-based regenerative therapies in patients, e.g., for a failing heart or Parkinson's...
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