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Primate Biology An international open-access journal on primate research
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PB | Articles | Volume 6, issue 2
Primate Biol., 6, 65–73, 2019
https://doi.org/10.5194/pb-6-65-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
Primate Biol., 6, 65–73, 2019
https://doi.org/10.5194/pb-6-65-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.

Research article 12 Jul 2019

Research article | 12 Jul 2019

Effect of ovariectomy on proximal tibia metaphysis and lumbar vertebral body in common marmoset monkeys

Christina Schlumbohm et al.
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Cited articles  
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Abbott, D. H., Barnett, D. K., Colman, R. J., Yamamoto, M. E., and Schultz-Darken, N. J.: Aspects of common marmoset basic biology and life history important for biomedical research, Comp. Med., 53, 339–350, 2003. 
Albright, F., Bloomberg, E., and Smith, P. H.: Post-menopausal osteoporosis, Tr. Assoc. Am. Physicians, 55, 298–305, 1940. 
Amstrup, A. K., Jakobsen, N. F. B., Moser, E., Sikjaer, T., Mosekilde, L., and Rejnmark, L.: Association between bone indices assessed by DXA, HRpQCT and QCT scans in postmenopausal women, J. Bone Miner. Metab., 34, 638–645, 2016. 
Angeliewa, A., Budde, M., Schlachter, M., Hoyle, N. R., and Bauss, F.: Biochemical bone turnover markers are useful tools to assess changes in bone metabolism in marmosetsm J. Bone. Miner. Metab., 22, 192–197, 2004. 
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We investigated the effect of estrogen withdrawal on bone tissue in adult female marmoset monkeys. Bone mineral density (BMD) of the proximal tibia and the second-last lumbar vertebral body was monitored before and up to 12 months after ovariectomy. All animals lost BMD in proximal tibia, but not in the vertebra. This supports the idea that ovariectomized marmoset monkeys may serve as a model for anti-osteoporosis drug testing.
We investigated the effect of estrogen withdrawal on bone tissue in adult female marmoset...
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