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Primate Biology An international open-access journal on primate research
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Volume 4, issue 1
Primate Biol., 4, 9–16, 2017
https://doi.org/10.5194/pb-4-9-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.

Special issue: Special diseases of nonhuman primates

Primate Biol., 4, 9–16, 2017
https://doi.org/10.5194/pb-4-9-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.

Research article 17 Feb 2017

Research article | 17 Feb 2017

Detection systems for antibody responses against herpes B virus

Stefan Pöhlmann et al.

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Transmission of macaque herpes B virus (BV) to humans can induce severe disease. Therefore, diagnostic tests for detecting BV infection are needed. Here, we show that antigens of BV-related non-human primate herpes viruses allow for the detection of antibodies elicited against BV with a higher sensitivity than antigens of human herpes simplex viruses (HSV). Moreover, we provide evidence that using recombinant viral glycoproteins may allow us to discriminate antibody responses against BV and HSV.
Transmission of macaque herpes B virus (BV) to humans can induce severe disease. Therefore,...
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