Journal cover Journal topic
Primate Biology An international open-access journal on primate research
Primate Biol., 4, 27-32, 2017
https://doi.org/10.5194/pb-4-27-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.
Research article
07 Mar 2017
Suspect Guillain-Barré syndrome in a male rhesus macaque (Macaca mulatta)
Tamara Becker1, Florian Pieper1, David Liebetanz2, Martina Bleyer1, Annette Schrod1, Kerstin Maetz-Rensing1, and Stefan Treue1 1German Primate Center, 37077 Göttingen, Germany
2Georg August University, University Hospital, 37075 Göttingen, Germany
Abstract. Guillain-Barré syndrome (GBS) is a rare, mainly acute inflammatory polyneuropathy in humans. It is frequently post-infectious with auto antibodies being formed against myelin sheaths, resulting in a progressive and more-or-less severe paralysis of the motor neuron and cranial nerves. Mortality is low and 60 % of the patients recover completely from the disease after intensive treatment.

In animals, there are a few diseases that closely resemble GBS, but cases of GBS in monkeys seem to be scarce. In this case report, the clinical course of a progressive tetraplegia in a male rhesus macaque is described. Clinical, cerebrospinal fluid (CSF), electroneurography (ENG) and electromyography (EMG), and pathological findings revealed symptoms very similar to human GBS.


Citation: Becker, T., Pieper, F., Liebetanz, D., Bleyer, M., Schrod, A., Maetz-Rensing, K., and Treue, S.: Suspect Guillain-Barré syndrome in a male rhesus macaque (Macaca mulatta), Primate Biol., 4, 27-32, https://doi.org/10.5194/pb-4-27-2017, 2017.
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